FBXO7 anticorps
Aperçu rapide pour FBXO7 anticorps (ABIN7114054)
Antigène
Voir toutes FBXO7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- FBXO7 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- F-box protein 7
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- FBXO7 (F-Box Protein 7 (FBXO7))
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Autre désignation
- FBXO7
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Sujet
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Synonyms: F-box only protein 7|FBXO7|FBX7
Background: Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy(mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.
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Poids moléculaire
- 58.5 kDa
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ID gène
- 25793
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UniProt
- Q9Y3I1
Antigène
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