SUPT16H anticorps

N° du produit ABIN7114058

L’anticorps Lapin Polyclonal anti-SUPT16H a été validé pour ELISA, WB, IHC et IP. Il convient pour détecter SUPT16H dans des échantillons de Humain et Souris.

Aperçu rapide pour SUPT16H anticorps (ABIN7114058)

Antigène: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUPT16H est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-SUPT16H anticorps

Fonction: SUPT16H antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: suppressor of Ty 16 homolog

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SUPT16H

Antigène: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Autre désignation: SUPT16H

Sujet:

Synonyms: FACT complex subunit SPT16|Chromatin-specific transcription elongation factor 140 kDa subunit|FACT 140 kDa subunit|FACTp140|Facilitates chromatin transcription complex subunit SPT16 (hSPT16)|SUPT16H|FACT140|FACTP140

Background: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2(casein kinase II).

Poids moléculaire: 140 kDa

ID gène: 6830

UniProt: Q9Y5B9

Pathways: Chromatin Binding