FAM20C anticorps (AA 102-330)

N° du produit ABIN7114089

Cet anticorps anti-FAM20C est un anticorps Lapin Polyclonal détectant FAM20C dans WB, ELISA et IHC. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour FAM20C anticorps (AA 102-330) (ABIN7114089)

Antigène: FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM20C est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-FAM20C anticorps

Épitope: AA 102-330

Fonction: FAM20C antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 102-330 aa

Immunogen: family with sequence similarity 20, member C

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur FAM20C

Antigène: FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))

Autre désignation: FAM20C

Sujet:

Synonyms: Extracellular serine/threonine protein kinase FAM20C|Dentin matrix protein 4 (DMP-4)|Golgi casein kinase|Golgi-enriched fraction casein kinase (GEF-CK)|FAM20C|DMP4

Background: Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth(PubMed:22582013, PubMed:23754375, PubMed:25789606). Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome(PubMed:26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity(PubMed:26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1(PubMed:22582013, PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion(PubMed:26091039).

Poids moléculaire: 50 kDa

ID gène: 56975

UniProt: Q8IXL6