Fibrillarin anticorps

N° du produit ABIN7114191

Cet anticorps anti-Fibrillarin est un anticorps Lapin Polyclonal détectant Fibrillarin dans WB, IHC, ELISA, IP et IF. Adapté pour Humain et Souris.

Aperçu rapide pour Fibrillarin anticorps (ABIN7114191)

Antigène: Fibrillarin (FBL)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fibrillarin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Détail du produit anti-Fibrillarin anticorps

Fonction: FBL antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: fibrillarin

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200, IP: 1:20 - 1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur Fibrillarin

Antigène: Fibrillarin (FBL)

Autre désignation: FBL

Sujet:

Synonyms: rRNA 2'-O-methyltransferase fibrillarin|34 kDa nucleolar scleroderma antigen|Histone-glutamine methyltransferase|U6 snRNA 2'-O-methyltransferase fibrillarin|FBL|FIB1|FLRN

Background: This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.

Poids moléculaire: 37 kDa

ID gène: 2091

UniProt: P22087

Pathways: Ribonucleoside Biosynthetic Process