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GEMIN5 anticorps

GEMIN5 Reactivité: Humain WB, IP, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7114527
  • Antigène Voir toutes GEMIN5 Anticorps
    GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
    Reactivité
    • 5
    • 1
    Humain
    Hôte
    • 5
    Lapin
    Clonalité
    • 5
    Polyclonal
    Conjugué
    • 5
    Cet anticorp GEMIN5 est non-conjugé
    Application
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    gem(nuclear organelle) associated protein 5
    Isotype
    IgG
    Top Product
    Discover our top product GEMIN5 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000, IP: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
    Autre désignation
    GEMIN5 (GEMIN5 Produits)
    Synonymes
    anticorps GEMIN-5, anticorps AA407055, anticorps AA407208, anticorps AI451603, anticorps BB194447, anticorps C330013N08, anticorps gem nuclear organelle associated protein 5, anticorps gem (nuclear organelle) associated protein 5, anticorps GEMIN5, anticorps Gemin5
    Sujet
    Synonyms: Background:The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. GEMIN5 acts as the snRNA-binding protein of the SMN complex.
    Poids moléculaire
    168 kDa
    ID gène
    25929
    UniProt
    Q8TEQ6
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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