GOT1 anticorps (AA 1-413)
Aperçu rapide pour GOT1 anticorps (AA 1-413) (ABIN7114620)
Antigène
Voir toutes GOT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-413
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Fonction
- GOT1 antibody
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Purification
- Protein A+G purification
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
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Immunogen sequence: 1-413aa
Immunogen: glutamic-oxaloacetic transaminase 1, soluble(aspartate aminotransferase 1)
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Isotype
- IgG2a
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Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- GOT1 (Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1) (GOT1))
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Autre désignation
- GOT1
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Sujet
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Synonyms: Aspartate aminotransferase, cytoplasmic (cAspAT)|Cysteine aminotransferase, cytoplasmic|Cysteine transaminase, cytoplasmic (cCAT)|Glutamate oxaloacetate transaminase 1|Transaminase A|GOT1
Background: Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase(3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.
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Poids moléculaire
- 43 kDa
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ID gène
- 2805
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UniProt
- P17174
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Pathways
- Hepatitis C, Monocarboxylic Acid Catabolic Process, Methionine Biosynthetic Process
Antigène
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