Glutaredoxin 1 anticorps

N° du produit ABIN7114634

L’anticorps Lapin Polyclonal anti-Glutaredoxin 1 a été validé pour WB, IHC et ELISA. Il convient pour détecter Glutaredoxin 1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Glutaredoxin 1 anticorps (ABIN7114634)

Antigène: Glutaredoxin 1 (GRX1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutaredoxin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Glutaredoxin 1 anticorps

Fonction: GLRX antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: glutaredoxin (thioltransferase)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur Glutaredoxin 1

Antigène: Glutaredoxin 1 (GRX1)

Autre désignation: GLRX

Sujet:

Synonyms: Glutaredoxin-1|Thioltransferase-1 (TTase-1)|GLRX|GRX

Background: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Poids moléculaire: 12 kDa

ID gène: 2745

UniProt: P35754

Pathways: Cell RedoxHomeostasis