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Histone H3.3 anticorps

Cet anticorps anti-Histone H3.3 est un anticorps Lapin Polyclonal détectant Histone H3.3 dans ELISA et WB. Adapté pour Humain, Souris et Rat.
N° du produit ABIN7114851

Aperçu rapide pour Histone H3.3 anticorps (ABIN7114851)

Antigène

Voir toutes Histone H3.3 (H3F3A) Anticorps
Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

Reactivité

  • 65
  • 15
  • 13
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 61
  • 7
Lapin

Clonalité

  • 50
  • 18
Polyclonal

Conjugué

  • 47
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Histone H3.3 est non-conjugé

Application

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  • 9
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  • 5
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  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB)
  • Fonction

    Histone H3.3 antibody

    Purification

    Immunogen affinity purified

    Pureté

    ≥95 % as determined by SDS-PAGE

    Immunogène

    H3 histone, family 3B(H3.3B)

    Isotype

    IgG
  • Indications d'application

    WB: 1:500-1:2000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze / thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    -20°C for 12 months

    Date de péremption

    12 months
  • Antigène

    Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

    Autre désignation

    Histone H3.3

    Sujet

    Synonyms: Histone H3.3|H3-3A|H3.3A|H3F3|H3F3A

    Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    Poids moléculaire

    17 kDa

    ID gène

    3021

    UniProt

    P84243
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