Histone H3.3 anticorps
Aperçu rapide pour Histone H3.3 anticorps (ABIN7114851)
Antigène
Voir toutes Histone H3.3 (H3F3A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Histone H3.3 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- H3 histone, family 3B(H3.3B)
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))
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Autre désignation
- Histone H3.3
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Sujet
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Synonyms: Histone H3.3|H3-3A|H3.3A|H3F3|H3F3A
Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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Poids moléculaire
- 17 kDa
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ID gène
- 3021
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UniProt
- P84243
Antigène
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