HEY1 anticorps

N° du produit ABIN7114852

Détail du produit anti-HEY1 anticorps

Antigène: HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HEY1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: hairy/enhancer-of-split related with YRPW motif 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IP: 1:200-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur HEY1

Antigène: HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))

Autre désignation: HEY1 (HEY1 Produits)

Synonymes: anticorps BHLHb31, anticorps CHF2, anticorps HERP2, anticorps HESR1, anticorps HRT-1, anticorps OAF1, anticorps AI316788, anticorps AI414254, anticorps HRT1, anticorps Herp2, anticorps Hesr1, anticorps bHLHb31, anticorps hesr-1, anticorps id:ibd1292, anticorps zgc:110572, anticorps bc8, anticorps chf2, anticorps herp2, anticorps hesr1, anticorps hrt1, anticorps oaf1, anticorps xbc8, anticorps hes related family bHLH transcription factor with YRPW motif 1, anticorps hairy/enhancer-of-split related with YRPW motif 1, anticorps hes-related family bHLH transcription factor with YRPW motif 1, anticorps hes related family bHLH transcription factor with YRPW motif 1 S homeolog, anticorps HEY1, anticorps Hey1, anticorps hey1, anticorps hey1.S

Sujet: Synonyms:BHLHB31, CHF2, HERP2, HESR1, HRT1 Background:Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'(PubMed:11095750). Downstream effector of Notch signaling required for cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY2 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3(PubMed:15485867). Involved in the regulation of liver cancer cells self-renewal(PubMed:25985737).

Poids moléculaire: 33 kDa

ID gène: 23462

UniProt: Q9Y5J3

Pathways: Tube Formation