HLTF anticorps
Aperçu rapide pour HLTF anticorps (ABIN7114924)
Antigène
Voir toutes HLTF AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- HLTF antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- helicase-like transcription factor
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- HLTF (Helicase-Like Transcription Factor (HLTF))
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Autre désignation
- HLTF
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Sujet
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Synonyms: Helicase-like transcription factor|DNA-binding protein/plasminogen activator inhibitor 1 regulator|HIP116|RING finger protein 80|RING-type E3 ubiquitin transferase HLTF|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3|Sucrose nonfermenting protein 2-like 3|HLTF|HIP116A|RNF80|SMARCA3|SNF2L3|ZBU1
Background: Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity, This activity may be required for transcriptional activation or repression of specific target promoters(By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair(PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.
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Poids moléculaire
- 114 kDa
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ID gène
- 6596
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UniProt
- Q14527
Antigène
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