HNRNPK anticorps
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- Antigène Voir toutes HNRNPK Anticorps
- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HNRNPK est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- heterogeneous nuclear ribonucleoprotein K
- Isotype
- IgG
- Top Product
- Discover our top product HNRNPK Anticorps primaire
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- Indications d'application
- WB: 1:500-1:2000, IP: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:10-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
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- Antigène
- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
- Autre désignation
- HNRNPK (HNRNPK Produits)
- Synonymes
- anticorps CSBP, anticorps HNRPK, anticorps TUNP, anticorps Csbp, anticorps Hnrpk, anticorps hnrpk, anticorps MGC75642, anticorps wu:fb37h02, anticorps wu:fi34c04, anticorps zgc:66162, anticorps KBBP, anticorps NOVA, anticorps heterogeneous nuclear ribonucleoprotein K, anticorps heterogeneous nuclear ribonucleoprotein K S homeolog, anticorps heterogeneous nuclear ribonucleoprotein k, anticorps HNRNPK, anticorps Hnrnpk, anticorps hnrnpk.S, anticorps hnrnpk, anticorps LOC5565718, anticorps CpipJ_CPIJ000130, anticorps NGK_p0004
- Sujet
- Synonyms:CSBP, hnRNP K, HNRNPK, HNRPK, TUNP Background:One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction(By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21(lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
- Poids moléculaire
- 51 kDa
- ID gène
- 3190
- UniProt
- P61978
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