HARS2 anticorps
Aperçu rapide pour HARS2 anticorps (ABIN7115030)
Antigène
Voir toutes HARS2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- HARS2 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- histidyl-tRNA synthetase 2, mitochondrial (putative)
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Isotype
- IgG
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Indications d'application
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- HARS2 (Histidyl-tRNA Synthetase 2, Mitochondrial (Putative) (HARS2))
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Autre désignation
- HARS2
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Sujet
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Synonyms: Histidine--tRNA ligase, mitochondrial|Histidine--tRNA ligase-like|Histidyl-tRNA synthetase (HisRS)|HARS2|HARSL|HARSR|HO3
Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene.
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Poids moléculaire
- 50 kDa
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ID gène
- 23438
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UniProt
- P49590
Antigène
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