HOMER1 anticorps

N° du produit ABIN7115100

Cet anticorps anti-HOMER1 est un anticorps Lapin Polyclonal détectant HOMER1 dans WB, ELISA, IHC, FACS et IP. Adapté pour Humain et Souris.

Aperçu rapide pour HOMER1 anticorps (ABIN7115100)

Antigène: HOMER1 (Homer Homolog 1 (HOMER1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HOMER1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP)

Détail du produit anti-HOMER1 anticorps

Fonction: HOMER1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: homer homolog 1(Drosophila)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur HOMER1

Antigène: HOMER1 (Homer Homolog 1 (HOMER1))

Autre désignation: HOMER1

Sujet:

Synonyms: Homer protein homolog 1 (Homer-1)|HOMER1|SYN47

Background: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development.

Poids moléculaire: 46-48 kDa

ID gène: 9456

UniProt: Q86YM7

Pathways: Skeletal Muscle Fiber Development