HCFC1 anticorps

N° du produit ABIN7115110

Cet anticorps Lapin Polyclonal détecte spécifiquement HCFC1 dans WB, IHC et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour HCFC1 anticorps (ABIN7115110)

Antigène: HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HCFC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-HCFC1 anticorps

Fonction: HCFC1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: host cell factor C1(VP16-accessory protein)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur HCFC1

Antigène: HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))

Autre désignation: HCFC1

Sujet:

Synonyms: Host cell factor 1 (HCF, HCF-1)|C1 factor|CFF|VCAF|VP16 accessory protein|HCF N-terminal chain 1|HCF N-terminal chain 2|HCF N-terminal chain 3|HCF N-terminal chain 4|HCF N-terminal chain 5|HCF N-terminal chain 6|HCF C-terminal chain 1|HCF C-terminal chain 2|HCF C-terminal chain 3|HCF C-terminal chain 4|HCF C-terminal chain 5|HCF C-terminal chain 6|HCFC1|HCF1|HFC1

Background: Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2, represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300. Coactivator for EGR2 and GABP2. Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase(H3K4me) and Sin3 histone deacetylase(HDAC) complexes(involved in the activation and repression of transcription, respectively) together. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. In case of human herpes simplex virus(HSV) infection, HCFC1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and POU2F1 thereby enabling the transcription of the viral immediate early genes.

Poids moléculaire: 230 kDa, 300 kDa

ID gène: 3054

UniProt: P51610