HTRA2 anticorps

N° du produit ABIN7115117

L’anticorps Lapin Polyclonal anti-HTRA2 a été validé pour WB, ELISA, IHC et IP. Il convient pour détecter HTRA2 dans des échantillons de Humain, Souris, Rat et Singe.

Aperçu rapide pour HTRA2 anticorps (ABIN7115117)

Antigène: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HTRA2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-HTRA2 anticorps

Fonction: HTRA2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: HtrA serine peptidase 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur HTRA2

Antigène: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Autre désignation: HTRA2

Sujet:

Synonyms: Serine protease HTRA2, mitochondrial|High temperature requirement protein A2 (HtrA2)|Omi stress-regulated endoprotease|Serine protease 25|Serine proteinase OMI|HTRA2|OMI|PRSS25

Background: Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins(also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.

Poids moléculaire: 36 kDa

ID gène: 27429

UniProt: O43464

Pathways: Positive Regulation of Endopeptidase Activity