IDS anticorps (AA 1-300)

N° du produit ABIN7115175

Cet anticorps anti-IDS est un anticorps Souris Monoclonal détectant IDS dans WB, IHC, ELISA et IF. Adapté pour Humain.

Aperçu rapide pour IDS anticorps (AA 1-300) (ABIN7115175)

Antigène: IDS (Iduronate 2-Sulfatase (IDS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IDS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: 2D2

Détail du produit anti-IDS anticorps

Épitope: AA 1-300

Fonction: IDS antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 1-300aa

Immunogen: iduronate 2-sulfatase

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur IDS

Antigène: IDS (Iduronate 2-Sulfatase (IDS))

Autre désignation: IDS

Sujet:

Synonyms: Iduronate 2-sulfatase|Alpha-L-iduronate sulfate sulfatase (Idursulfase)|Iduronate 2-sulfatase 42 kDa chain|Iduronate 2-sulfatase 14 kDa chain|IDS|SIDS

Background: Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181).

Poids moléculaire: 76 kDa, 55 kDa

ID gène: 3423

UniProt: P22304

Pathways: Glycosaminoglycan Metabolic Process