Importin 11 anticorps

N° du produit ABIN7115208

Cet anticorps anti-Importin 11 est un anticorps Lapin Polyclonal détectant Importin 11 dans WB, ELISA et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Importin 11 anticorps (ABIN7115208)

Antigène: Importin 11 (IPO11)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Importin 11 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Importin 11 anticorps

Fonction: IPO11 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: importin 11

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur Importin 11

Antigène: Importin 11 (IPO11)

Autre désignation: IPO11

Sujet:

Synonyms: Importin-11 (Imp11)|Ran-binding protein 11 (RanBP11)|IPO11|RANBP11

Background: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals(NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex(NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus(By similarity). Mediates the nuclear import of UBE2E3, and of RPL12(By similarity).

Poids moléculaire: 112 kDa

ID gène: 51194

UniProt: Q9UI26

Pathways: Protein targeting to Nucleus