Importin 11 anticorps

N° du produit ABIN7115208

Détail du produit anti-Importin 11 anticorps

Antigène: Importin 11 (IPO11)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Importin 11 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: importin 11

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur Importin 11

Antigène: Importin 11 (IPO11)

Autre désignation: IPO11 (IPO11 Produits)

Synonymes: anticorps MGC83107, anticorps IPO11, anticorps slrn, anticorps ranbp11, anticorps RanBP11, anticorps 1700081H05Rik, anticorps 2510001A17Rik, anticorps AI314624, anticorps AW555235, anticorps E330021B14Rik, anticorps Ranbp11, anticorps importin 11 S homeolog, anticorps importin 11, anticorps importin-11, anticorps ipo11.S, anticorps ipo11, anticorps IPO11, anticorps AFUA_1G03590, anticorps BDBG_04626, anticorps LOC100162908, anticorps Ipo11

Sujet: Synonyms:RANBP11 Background:Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals(NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex(NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus(By similarity). Mediates the nuclear import of UBE2E3, and of RPL12(By similarity).

Poids moléculaire: 112 kDa

ID gène: 51194

UniProt: Q9UI26

Pathways: Protein targeting to Nucleus