IVNS1ABP anticorps

N° du produit ABIN7115224

Cet anticorps Lapin Polyclonal détecte spécifiquement IVNS1ABP dans WB, IHC et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour IVNS1ABP anticorps (ABIN7115224)

Antigène: IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IVNS1ABP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-IVNS1ABP anticorps

Fonction: IVNS1ABP antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: influenza virus NS1A binding protein

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur IVNS1ABP

Antigène: IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Autre désignation: IVNS1ABP

Classe de substances: Influenza Protein

Sujet:

Synonyms: Influenza virus NS1A-binding protein (NS1-BP, NS1-binding protein)|Aryl hydrocarbon receptor-associated protein 3|Kelch-like protein 39|IVNS1ABP|ARA3|FLARA3|KIAA0850|KLHL39|NS1|NS1BP

Background: Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization, Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines(By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing, may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.

Poids moléculaire: 70 kDa

ID gène: 10625

UniProt: Q9Y6Y0

Pathways: Negative Regulation of intrinsic apoptotic Signaling