ING3 anticorps

N° du produit ABIN7115236

Cet anticorps Lapin Polyclonal détecte spécifiquement ING3 dans WB, ELISA et IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour ING3 anticorps (ABIN7115236)

Antigène: ING3 (Inhibitor of Growth Family, Member 3 (ING3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ING3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-ING3 anticorps

Fonction: ING3 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: inhibitor of growth family, member 3

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ING3

Antigène: ING3 (Inhibitor of Growth Family, Member 3 (ING3))

Autre désignation: ING3

Sujet:

Synonyms: Inhibitor of growth protein 3|p47ING3|ING3

Background: Component of the NuA4 histone acetyltransferase(HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.

Poids moléculaire: 47 kDa

ID gène: 54556

UniProt: Q9NXR8