INO80 anticorps
Aperçu rapide pour INO80 anticorps (ABIN7115249)
Antigène
Voir toutes INO80 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- INO80 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- INO80 homolog
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- INO80 (INO80 Homolog (INO80))
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Autre désignation
- INO80
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Sujet
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Synonyms: Chromatin-remodeling ATPase INO80 (hINO80)|DNA helicase-related INO80 complex homolog 1|DNA helicase-related protein INO80|INO80 complex subunit A|INO80|INO80A|INOC1|KIAA1259
Background: DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair, according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double-stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle.
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Poids moléculaire
- 177, 150 kDa
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ID gène
- 54617
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UniProt
- Q9ULG1
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Pathways
- Positive Regulation of Response to DNA Damage Stimulus
Antigène
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