IFITM1 anticorps

N° du produit ABIN7115386

Cet anticorps Lapin Polyclonal détecte spécifiquement IFITM1 dans WB, ELISA, IHC et IP. Il présente une réactivité envers Humain.

Aperçu rapide pour IFITM1 anticorps (ABIN7115386)

Antigène: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFITM1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-IFITM1 anticorps

Fonction: IFITM1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: interferon induced transmembrane protein 1(9-27)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur IFITM1

Antigène: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Autre désignation: IFITM1

Sujet:

Synonyms: Interferon-induced transmembrane protein 1|Dispanin subfamily A member 2a (DSPA2a)|Interferon-induced protein 17|Interferon-inducible protein 9-27|Leu-13 antigen|IFITM1|CD225|IFI17

Background: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus(SARS-CoV), Marburg virus(MARV), Ebola virus(EBOV), Dengue virus(DNV), West Nile virus(WNV), human immunodeficiency virus type 1(HIV-1) and hepatitis C virus(HCV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation.

Poids moléculaire: 17-19 kDa

ID gène: 8519

UniProt: P13164