IQCB1 anticorps

N° du produit ABIN7115509

Cet anticorps Lapin Polyclonal détecte spécifiquement IQCB1 dans ELISA et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour IQCB1 anticorps (ABIN7115509)

Antigène: IQCB1 (IQ Motif Containing B1 (IQCB1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IQCB1 est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Détail du produit anti-IQCB1 anticorps

Fonction: IQCB1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: IQ motif containing B1

Isotype: IgG

Information d'application

Indications d'application: IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur IQCB1

Antigène: IQCB1 (IQ Motif Containing B1 (IQCB1))

Autre désignation: IQCB1

Sujet:

Synonyms: IQ calmodulin-binding motif-containing protein 1|Nephrocystin-5|p53 and DNA damage-regulated IQ motif protein (PIQ)|IQCB1|KIAA0036|NPHP5

Background: IQCB1, also known as NPHP5, is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. It has a central coiled-coil region and two calmodulin-binding IQ domains. Localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells, IQCB1 is thought to play a role in ciliary function. Mutations in this gene result in Senior-Loken syndrome type 5, a juvenile disorder characterized by defects in the waste filtering system of the kidney, as well as retinal degradation.

UniProt: Q15051