IQCB1 anticorps

N° du produit ABIN7115509

Détail du produit anti-IQCB1 anticorps

Antigène: IQCB1 (IQ Motif Containing B1 (IQCB1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IQCB1 est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: IQ motif containing B1

Isotype: IgG

Information d'application

Indications d'application: IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur IQCB1

Antigène: IQCB1 (IQ Motif Containing B1 (IQCB1))

Autre désignation: NPHP5,IQCB1 (IQCB1 Produits)

Synonymes: anticorps piq, anticorps nphp5, anticorps slsn5, anticorps MGC81507, anticorps IQCB1, anticorps zgc:101792, anticorps MGC146213, anticorps 6820449I09Rik, anticorps AV128382, anticorps NPHP5, anticorps PIQ, anticorps SLSN5, anticorps IQ motif containing B1, anticorps IQ motif containing B1 L homeolog, anticorps IQ calmodulin-binding motif containing 1, anticorps Iqcb1, anticorps iqcb1.L, anticorps IQCB1, anticorps iqcb1

Sujet: Synonyms:IQ motif containing B1, IQCB1, KIAA0036, Nephrocystin 5, NPHP5, PIQ, SLSN5 Background:IQCB1, also known as NPHP5, is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. It has a central coiled-coil region and two calmodulin-binding IQ domains. Localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells, IQCB1 is thought to play a role in ciliary function. Mutations in this gene result in Senior-Loken syndrome type 5, a juvenile disorder characterized by defects in the waste filtering system of the kidney, as well as retinal degradation.

UniProt: Q15051