KPNA1 anticorps

N° du produit ABIN7115572

Cet anticorps Lapin Polyclonal détecte spécifiquement KPNA1 dans WB, ELISA, IHC et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour KPNA1 anticorps (ABIN7115572)

Antigène: KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KPNA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-KPNA1 anticorps

Fonction: KPNA1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: karyopherin alpha 1 (importin alpha 5)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur KPNA1

Antigène: KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))

Autre désignation: KPNA1

Sujet:

Synonyms: Importin subunit alpha-5|Karyopherin subunit alpha-1|Nucleoprotein interactor 1 (NPI-1)|RAG cohort protein 2|SRP1-beta|Importin subunit alpha-5, N-terminally processed|KPNA1|RCH2

Background: The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 66 kDa

ID gène: 3836

UniProt: P52294

Pathways: M Phase, Protein targeting to Nucleus