KNG1 anticorps

N° du produit ABIN7115720

L’anticorps Lapin Polyclonal anti-KNG1 a été validé pour WB, ELISA et IF. Il convient pour détecter KNG1 dans des échantillons de Humain et Souris.

Aperçu rapide pour KNG1 anticorps (ABIN7115720)

Antigène: KNG1 (Kininogen 1 (KNG1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KNG1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-KNG1 anticorps

Fonction: KNG1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: Kininogen-1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IF: 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur KNG1

Antigène: KNG1 (Kininogen 1 (KNG1))

Autre désignation: KNG1

Sujet:

Synonyms: Kininogen-1|Alpha-2-thiol proteinase inhibitor|Fitzgerald factor|High molecular weight kininogen (HMWK)|Williams-Fitzgerald-Flaujeac factor|Kininogen-1 heavy chain|T-kinin Alternative names: Ile-Ser-Bradykinin|Bradykinin Alternative names: Kallidin I|Lysyl-bradykinin Alternative names: Kallidin II|Kininogen-1 light chain|Low molecular weight growth-promoting factor|KNG1|BDK|KNG

Background: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 68 kDa

ID gène: 3827

UniProt: P01042

Pathways: ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process