KLF10/TIEG1 anticorps
Aperçu rapide pour KLF10/TIEG1 anticorps (ABIN7115728)
Antigène
Voir toutes KLF10/TIEG1 (KLF10) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- KLF10 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- Kruppel-like factor 10
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- KLF10/TIEG1 (KLF10) (Kruppel-Like Factor 10 (KLF10))
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Autre désignation
- KLF10
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Sujet
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Synonyms: Krueppel-like factor 10|EGR-alpha|Transforming growth factor-beta-inducible early growth response protein 1 (TGFB-inducible early growth response protein 1, TIEG-1)|KLF10|TIEG|TIEG1
Background: Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock, binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis(By similarity). May play a role in the cell cycle regulation.
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Poids moléculaire
- 52 kDa
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ID gène
- 7071
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UniProt
- Q13118
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Pathways
- Stem Cell Maintenance
Antigène
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