LRSAM1 anticorps

N° du produit ABIN7115802

Cet anticorps anti-LRSAM1 Polyclonal Lapin (ABIN7115802) détecte spécifiquement LRSAM1 dans WB, IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour LRSAM1 anticorps (ABIN7115802)

Antigène: LRSAM1 (Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRSAM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-LRSAM1 anticorps

Fonction: LRSAM1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: leucine rich repeat and sterile alpha motif containing 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur LRSAM1

Antigène: LRSAM1 (Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1))

Autre désignation: LRSAM1

Sujet:

Synonyms: E3 ubiquitin-protein ligase LRSAM1|Leucine-rich repeat and sterile alpha motif-containing protein 1|RING-type E3 ubiquitin transferase LRSAM1|Tsg101-associated ligase (hTAL)|LRSAM1|TAL

Background: E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic(EGF receptors) and exocytic(HIV-1 viral proteins) cargos(PubMed:15256501). Bacterial recognition protein that defends the cytoplasm from invasive pathogens(PubMed:23245322). Localizes to several intracellular bacterial pathogens and generates the bacteria-associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation(xenophagy)(PubMed:23245322, PubMed:25484098).

Poids moléculaire: 84 kDa

ID gène: 90678

UniProt: Q6UWE0