LRRC8D anticorps

N° du produit ABIN7115814

Cet anticorps anti-LRRC8D est un anticorps Lapin Polyclonal détectant LRRC8D dans ELISA et WB. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour LRRC8D anticorps (ABIN7115814)

Antigène: LRRC8D (Leucine Rich Repeat Containing 8 Family, Member D (LRRC8D))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC8D est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-LRRC8D anticorps

Fonction: LRRC8D antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: leucine rich repeat containing 8 family, member D

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur LRRC8D

Antigène: LRRC8D (Leucine Rich Repeat Containing 8 Family, Member D (LRRC8D))

Autre désignation: LRRC8D

Sujet:

Synonyms: Volume-regulated anion channel subunit LRRC8D|Leucine-rich repeat-containing protein 5|Leucine-rich repeat-containing protein 8D (HsLRRC8D)|LRRC8D|LRRC5

Background: Non-essential component of the volume-regulated anion channel(VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member(LRRC8B, LRRC8C, LRRC8D or LRRC8E), channel characteristics depend on the precise subunit composition(PubMed:24790029, PubMed:26824658). LRRC8A and LRRC8D are required for the uptake of the drug cisplatin(PubMed:26530471). Mediates the import of the antibiotic blasticidin-S into the cell(PubMed:24782309).

Poids moléculaire: 98-120 kDa

ID gène: 55144

UniProt: Q7L1W4