LRRC8D anticorps

N° du produit ABIN7115814

Détail du produit anti-LRRC8D anticorps

Antigène: LRRC8D (Leucine Rich Repeat Containing 8 Family, Member D (LRRC8D))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC8D est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: leucine rich repeat containing 8 family, member D

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur LRRC8D

Antigène: LRRC8D (Leucine Rich Repeat Containing 8 Family, Member D (LRRC8D))

Autre désignation: LRRC8D (LRRC8D Produits)

Synonymes: anticorps LRRC5, anticorps 2810473G09Rik, anticorps 4930525N13Rik, anticorps A930019F03, anticorps Lrrc5, anticorps LRRC8D, anticorps DKFZp469O1725, anticorps lrrc8d, anticorps zgc:153223, anticorps leucine rich repeat containing 8 VRAC subunit D, anticorps leucine rich repeat containing 8D, anticorps leucine rich repeat containing 8 family member D, anticorps leucine rich repeat containing 8 VRAC subunit Db, anticorps LRRC8D, anticorps Lrrc8d, anticorps lrrc8d, anticorps lrrc8db

Sujet: Synonyms:LRRC5 Background:Non-essential component of the volume-regulated anion channel(VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member(LRRC8B, LRRC8C, LRRC8D or LRRC8E), channel characteristics depend on the precise subunit composition(PubMed:24790029, PubMed:26824658). LRRC8A and LRRC8D are required for the uptake of the drug cisplatin(PubMed:26530471). Mediates the import of the antibiotic blasticidin-S into the cell(PubMed:24782309).

Poids moléculaire: 98-120 kDa

ID gène: 55144

UniProt: Q7L1W4