LRWD1 anticorps

N° du produit ABIN7115828

L’anticorps anti-LRWD1 Polyclonal Lapin est utilisé pour la détection de LRWD1 dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour LRWD1 anticorps (ABIN7115828)

Antigène: LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRWD1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-LRWD1 anticorps

Fonction: LRWD1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: leucine-rich repeats and WD repeat domain containing 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur LRWD1

Antigène: LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))

Autre désignation: LRWD1

Sujet:

Synonyms: Leucine-rich repeat and WD repeat-containing protein 1|Centromere protein 33 (CENP-33)|Origin recognition complex-associated protein (ORC-associated protein, ORCA)|LRWD1|CENP-33|ORCA

Background: Required for G1/S transition. Recruits and stabilizes the origin recognition complex(ORC) onto chromatin during G1 to establish pre-replication complex(preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.

Poids moléculaire: 85 kDa

ID gène: 222229

UniProt: Q9UFC0

Pathways: Chromatin Binding