Leupaxin anticorps
Aperçu rapide pour Leupaxin anticorps (ABIN7115856)
Antigène
Voir toutes Leupaxin (LPXN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- LPXN antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- leupaxin
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- Leupaxin (LPXN)
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Autre désignation
- LPXN
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Sujet
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Synonyms: Leupaxin|LPXN|LDLP
Background: Transcriptional coactivator for androgen receptor(AR) and serum response factor(SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin-induced tyrosine phosphorylation of paxillin(PXN). May play a critical role as an adapter protein in the formation of the adhesion zone in osteoclasts. Negatively regulates B-cell antigen receptor(BCR) signaling.
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Poids moléculaire
- 50-60 kDa
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ID gène
- 9404
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UniProt
- O60711
Antigène
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