LIMS1 anticorps

N° du produit ABIN7115864

L’anticorps Lapin Polyclonal anti-LIMS1 a été validé pour WB, ELISA, IHC et IF. Il convient pour détecter LIMS1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour LIMS1 anticorps (ABIN7115864)

Antigène: LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIMS1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-LIMS1 anticorps

Fonction: LIMS1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: LIM and senescent cell antigen-like domains 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur LIMS1

Antigène: LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))

Autre désignation: LIMS1

Sujet:

Synonyms: LIM and senescent cell antigen-like-containing domain protein 1|Particularly interesting new Cys-His protein 1 (PINCH-1)|Renal carcinoma antigen NY-REN-48|LIMS1|PINCH|PINCH1

Background: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 40 kDa

ID gène: 3987

UniProt: P48059