LIN7A anticorps

N° du produit ABIN7115884

Cet anticorps Lapin Polyclonal détecte spécifiquement LIN7A dans WB, ELISA, IP et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour LIN7A anticorps (ABIN7115884)

Antigène: LIN7A (Lin-7 Homolog A (LIN7A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIN7A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (IHC)

Détail du produit anti-LIN7A anticorps

Fonction: LIN7A antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: lin-7 homolog A(C. elegans)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur LIN7A

Antigène: LIN7A (Lin-7 Homolog A (LIN7A))

Autre désignation: LIN7A

Sujet:

Synonyms: Protein lin-7 homolog A (Lin-7A, hLin-7)|Mammalian lin-seven protein 1 (MALS-1)|Tax interaction protein 33 (TIP-33)|Vertebrate lin-7 homolog 1 (Veli-1)|LIN7A|MALS1|VELI1

Background: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7(LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B(subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter(SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

Poids moléculaire: 28-30 kDa

ID gène: 8825

UniProt: O14910

Pathways: Synaptic Membrane