LONP1 anticorps

N° du produit ABIN7115913

Cet anticorps anti-LONP1 est un anticorps Souris Monoclonal détectant LONP1 dans WB, ELISA, IHC et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour LONP1 anticorps (ABIN7115913)

Antigène: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LONP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 9H10

Détail du produit anti-LONP1 anticorps

Fonction: LONP1 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: lon peptidase 1, mitochondrial

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:500-1:10000, IHC: 1:400-1:1600, IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur LONP1

Antigène: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Autre désignation: LONP1

Sujet:

Synonyms: Lon protease homolog, mitochondrial|LONHs|Lon protease-like protein (LONP)|Mitochondrial ATP-dependent protease Lon|Serine protease 15|LONP1|PRSS15

Background: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory(StAR) protein.

Poids moléculaire: 100 kDa

ID gène: 9361

UniProt: P36776