LOXL1 anticorps
Aperçu rapide pour LOXL1 anticorps (ABIN7115988)
Antigène
Voir toutes LOXL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- LOXL1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- lysyl oxidase-like 1
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Isotype
- IgG
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Indications d'application
- WB: 1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))
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Autre désignation
- LOXL1
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Sujet
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Synonyms: Lysyl oxidase homolog 1|Lysyl oxidase-like protein 1 (LOL)|LOXL1|LOXL
Background: This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.
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Poids moléculaire
- 70 kDa
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ID gène
- 4016
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UniProt
- Q08397
Antigène
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