MAGEA3 anticorps

N° du produit ABIN7116156

Cet anticorps anti-MAGEA3 est un anticorps Souris Monoclonal détectant MAGEA3 dans WB, ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour MAGEA3 anticorps (ABIN7116156)

Antigène: MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MAGEA3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 4E9

Détail du produit anti-MAGEA3 anticorps

Fonction: MAGEA3 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: melanoma antigen family A, 3

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur MAGEA3

Antigène: MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))

Autre désignation: MAGEA3

Sujet:

Synonyms: Melanoma-associated antigen 3|Antigen MZ2-D|Cancer/testis antigen 1.3 (CT1.3)|MAGE-3 antigen|MAGEA3|MAGE3

Background: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Poids moléculaire: 35-55 kDa

ID gène: 4102

UniProt: P43357