NG2 anticorps

N° du produit ABIN7116175

Cet anticorps Lapin Polyclonal détecte spécifiquement NG2 dans WB, IHC et ELISA. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour NG2 anticorps (ABIN7116175)

Antigène: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NG2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-NG2 anticorps

Fonction: CSPG4 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: chondroitin sulfate proteoglycan 4

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC: 1:50-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur NG2

Antigène: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Autre désignation: CSPG4

Sujet:

Synonyms: Chondroitin sulfate proteoglycan 4|Chondroitin sulfate proteoglycan NG2|Melanoma chondroitin sulfate proteoglycan|Melanoma-associated chondroitin sulfate proteoglycan|CSPG4|MCSP

Background: CSPG4, also named as HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16 and NG2, is a proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. CSPG4 may inhibit neurite outgrowth and growth cone collapse during axon regeneration. It is cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. CSPG4 may regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. It modulates the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin.

Poids moléculaire: 240-250 kDa

ID gène: 1464

UniProt: Q6UVK1

Pathways: Glycosaminoglycan Metabolic Process