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MARCHF8 anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement dans ELISA, WB et IP. Il présente une réactivité envers Humain, Souris et Rat.
N° du produit ABIN7116199

Aperçu rapide pour MARCHF8 anticorps (ABIN7116199)

Antigène

MARCHF8

Reactivité

Humain, Souris, Rat

Hôte

  • 1
Lapin

Clonalité

  • 1
Polyclonal

Conjugué

  • 1
Inconjugué

Application

ELISA, Western Blotting (WB), Immunoprecipitation (IP)
  • Fonction

    MARCHF8 antibody

    Purification

    Immunogen affinity purified

    Pureté

    ≥95 % as determined by SDS-PAGE

    Immunogène

    membrane-associated ring finger(C3HC4) 8

    Isotype

    IgG
  • Indications d'application

    WB: 1:500-1:1000, IP: 1:200-1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze / thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    -20°C for 12 months

    Date de péremption

    12 months
  • Antigène

    MARCHF8

    Sujet

    Synonyms: E3 ubiquitin-protein ligase MARCHF8|Cellular modulator of immune recognition (c-MIR)|Membrane-associated RING finger protein 8|Membrane-associated RING-CH protein VIII (MARCH-VIII)|RING finger protein 178|RING-type E3 ubiquitin transferase MARCHF8|MARCHF8|MARCH8|MIR|RNF178

    Background: E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. May also promote ubiquitination and endocytosis of TFRC and FAS.

    Poids moléculaire

    33 kDa

    ID gène

    220972

    UniProt

    Q5T0T0
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