MARCHF8 anticorps
Aperçu rapide pour MARCHF8 anticorps (ABIN7116199)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- MARCHF8 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- membrane-associated ring finger(C3HC4) 8
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:1000, IP: 1:200-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- MARCHF8
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Sujet
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Synonyms: E3 ubiquitin-protein ligase MARCHF8|Cellular modulator of immune recognition (c-MIR)|Membrane-associated RING finger protein 8|Membrane-associated RING-CH protein VIII (MARCH-VIII)|RING finger protein 178|RING-type E3 ubiquitin transferase MARCHF8|MARCHF8|MARCH8|MIR|RNF178
Background: E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. May also promote ubiquitination and endocytosis of TFRC and FAS.
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Poids moléculaire
- 33 kDa
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ID gène
- 220972
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UniProt
- Q5T0T0
Antigène
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