MACF1 anticorps

N° du produit ABIN7116291

Cet anticorps anti-MACF1 est un anticorps Lapin Polyclonal détectant MACF1 dans ELISA, IHC et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour MACF1 anticorps (ABIN7116291)

Antigène: MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MACF1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MACF1 anticorps

Fonction: MACF1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: microtubule-actin crosslinking factor 1

Isotype: IgG

Information d'application

Indications d'application: IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur MACF1

Antigène: MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))

Autre désignation: MACF1

Sujet:

Synonyms: Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5|620 kDa actin-binding protein (ABP620)|Actin cross-linking family protein 7|Macrophin-1|Trabeculin-alpha|MACF1|ABP620|ACF7|KIAA0465|KIAA0754|KIAA1251

Background: Isoform 2 is a F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex(composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions(FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells(By similarity).

Poids moléculaire: 83 kDa

ID gène: 23499

UniProt: Q9UPN3