MLXIP anticorps

N° du produit ABIN7116474

Cet anticorps anti-MLXIP est un anticorps Lapin Polyclonal détectant MLXIP dans ELISA, WB, IHC et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour MLXIP anticorps (ABIN7116474)

Antigène: MLXIP (MLX Interacting Protein (MLXIP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLXIP est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MLXIP anticorps

Fonction: MLXIP antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: MLX interacting protein

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur MLXIP

Antigène: MLXIP (MLX Interacting Protein (MLXIP))

Autre désignation: MLXIP

Sujet:

Synonyms: MLX-interacting protein|Class E basic helix-loop-helix protein 36 (bHLHe36)|Transcriptional activator MondoA|MLXIP|BHLHE36|KIAA0867|MIR|MONDOA

Background: Mlx-interacting protein(MLXIP), after forming heterodimers with MLX, can bind to and then activate transcription from CACGTG E boxes. The N terminus of MLXIP acts as a CRM1-dependent nuclear export signal and contribute to the cytoplasmic localization of the complex, and as a binding site for 13 protein. the C terminus contains a cytoplasmic localization signal and mediates protein-protein interaction of MONDOA and MLX. The complex play a role in transcriptional activation of glycolytic target genes and glucose-responsive gene regulation. This antibody could recognize isoform1(~110kd) and isoform3(~69kd) of MLXIP. A specific MLXIP of approximately 130 kDa was detected. It demonstrates that MLXIP associated specifically with Mlx in the cytoplasm (PMID: 11073985).

Poids moléculaire: 130 kDa

ID gène: 22877

UniProt: Q9HAP2