MLF1 anticorps
Aperçu rapide pour MLF1 anticorps (ABIN7116570)
Antigène
Voir toutes MLF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- MLF1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- myeloid leukemia factor 1
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- MLF1 (Myeloid Leukemia Factor 1 (MLF1))
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Autre désignation
- MLF1
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Sujet
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Synonyms: Myeloid leukemia factor 1|Myelodysplasia-myeloid leukemia factor 1|MLF1
Background: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
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Poids moléculaire
- 38 kDa
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UniProt
- P58340
Antigène
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