MYO9B anticorps

N° du produit ABIN7116615

Cet anticorps anti-MYO9B est un anticorps Lapin Polyclonal détectant MYO9B dans WB, ELISA et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour MYO9B anticorps (ABIN7116615)

Antigène: MYO9B (Myosin IXB (MYO9B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYO9B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-MYO9B anticorps

Fonction: MYO9B antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: myosin IXB

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur MYO9B

Antigène: MYO9B (Myosin IXB (MYO9B))

Autre désignation: MYO9B

Sujet:

Synonyms: Unconventional myosin-IXb|Unconventional myosin-9b|MYO9B|MYR5

Background: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions(PubMed:9490638). Also acts as a GTPase activator for RHOA(PubMed:9490638, PubMed:26529257). Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. This is regulated by its interaction with the SLIT2 receptor ROBO1, interaction with ROBO1 impairs interaction with RHOA and subsequent activation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA(PubMed:26529257).

Poids moléculaire: 230-250 kDa

ID gène: 4650

UniProt: Q13459