MX1 anticorps
Aperçu rapide pour MX1 anticorps (ABIN7116666)
Antigène
Voir toutes MX1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- MX1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- Myxovirus resistance protein 1
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- MX1 (Myxovirus Resistance Protein 1 (MX1))
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Autre désignation
- MX1
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Sujet
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Synonyms: Interferon-induced GTP-binding protein Mx1|Interferon-induced protein p78 (IFI-78K)|Interferon-regulated resistance GTP-binding protein MxA|Myxoma resistance protein 1|Myxovirus resistance protein 1|Interferon-induced GTP-binding protein Mx1, N-terminally processed|MX1
Background: Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus(THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus(LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus(IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.
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Poids moléculaire
- 76 kDa
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ID gène
- 4599
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UniProt
- P20591
Antigène
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