NDC80 anticorps

N° du produit ABIN7116759

Cet anticorps anti-NDC80 est un anticorps Lapin Polyclonal détectant NDC80 dans WB, ELISA, IHC et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour NDC80 anticorps (ABIN7116759)

Antigène: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NDC80 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-NDC80 anticorps

Fonction: NDC80 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: NDC80 homolog, kinetochore complex component

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur NDC80

Antigène: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Autre désignation: NDC80

Sujet:

Synonyms: Kinetochore protein NDC80 homolog|Highly expressed in cancer protein|Kinetochore protein Hec1 (HsHec1)|Kinetochore-associated protein 2|Retinoblastoma-associated protein HEC|NDC80|HEC|HEC1|KNTC2

Background: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity(PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore(PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules(PubMed:23085020).

Poids moléculaire: 76 kDa

ID gène: 10403

UniProt: O14777

Pathways: Maintenance of Protein Location