Neudesin anticorps
Aperçu rapide pour Neudesin anticorps (ABIN7116786)
Antigène
Voir toutes Neudesin (NENF) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- NENF antibody
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Purification
- Protein A+G purification
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- neuron derived neurotrophic factor
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Isotype
- IgG2a
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Indications d'application
- WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:50-1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- Neudesin (NENF)
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Autre désignation
- NENF
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Sujet
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Synonyms: Neudesin|Cell immortalization-related protein 2|Neuron-derived neurotrophic factor|Protein GIG47|Secreted protein of unknown function (SPUF protein)|NENF|CIR2|SPUF
Background: Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance(By similarity). Plays a role in the human tumorigenesis(PubMed:22748190).
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Poids moléculaire
- 18 kDa
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ID gène
- 29937
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UniProt
- Q9UMX5
Antigène
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