CD56 anticorps

N° du produit ABIN7116789

Cet anticorps anti-CD56 est un anticorps Souris Monoclonal détectant CD56 dans WB, IHC et ELISA. Adapté pour Humain et Souris.

Aperçu rapide pour CD56 anticorps (ABIN7116789)

Antigène: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD56 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 0D10

Détail du produit anti-CD56 anticorps

Fonction: NCAM1 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: neural cell adhesion molecule 1

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:1000-1:10000, IHC: 1:200-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CD56

Antigène: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Autre désignation: NCAM1

Sujet:

Synonyms: Neural cell adhesion molecule 1 (N-CAM-1, NCAM-1)|NCAM1|NCAM

Background: Neural cell adhesion molecule 1(NCAM1, also known as CD56) is a cell adhesion glycoprotein of the immunoglobulin(Ig) superfamily. It is a multifunction protein involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM1 is expressed on human neurones, glial cells, skeletal muscle cells, NK cells and a subset of T cells, and the expression is observed in a wide variety human tumors, including myeloma, myeloid leukemia, neuroendocrine tumors, Wilms' tumor, neuroblastoma, and NK/T cell lymphomas. Three major isoforms of NCAM1, with molecular masses of 120, 140, and 180 kDa, are generated by alternative splicing of mRNA(PMID: 9696812). The glycosylphosphatidylinositol(GPI)-anchored NCAM120 and the transmembrane NCAM140 and NCAM180 consist of five Ig-like domains and two fibronection-type III repeats(FNIII). All three forms can be posttranslationally modified by addition of polysialic acid(PSA)(PMID: 14976519). Several other isofroms have also been described(PMID: 1856291).

Poids moléculaire: 140 kDa

ID gène: 4684

UniProt: P13591