NMNAT3 anticorps
Aperçu rapide pour NMNAT3 anticorps (ABIN7116866)
Antigène
Voir toutes NMNAT3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- NMNAT3 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- nicotinamide nucleotide adenylyltransferase 3
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))
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Autre désignation
- NMNAT3
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Sujet
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Synonyms: Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 (NMN/NaMN adenylyltransferase 3)|Nicotinamide-nucleotide adenylyltransferase 3 (NMN adenylyltransferase 3)|Nicotinate-nucleotide adenylyltransferase 3 (NaMN adenylyltransferase 3)|Pyridine nucleotide adenylyltransferase 3 (PNAT-3)|NMNAT3
Background: Catalyzes the formation of NAD(+) from nicotinamide mononucleotide(NMN) and ATP. Can also use the deamidated form, nicotinic acid mononucleotide(NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate(TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD(+), NADH, NaAD, nicotinic acid adenine dinucleotide phosphate(NHD), nicotinamide guanine dinucleotide(NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+). Protects against axonal degeneration following injury.
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Poids moléculaire
- 24-28 kDa
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ID gène
- 349565
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UniProt
- Q96T66
Antigène
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